After a trying day of Dee Dee's lunacy, Dexter calls her into his office and tells her that she's fired. Although he ends up getting a lot more work done, he discovers that peace, quiet, and solitude don't really make him happy, so he does the logical thing and starts accepting applications for troublesome older sisters.
After many dissipointing applicants, Dexter hires a beautiful blonde woman. He tries to teach her how to act more like Dee Dee. However his attraction to the woman makes it difficult, and she ends up quitting when she finds out that Dexter is a real little boy with a secret lab rather than a tv show with a similiar premise.